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中文名称：OSBPL2抗原（重组蛋白）
英文名称： OSBPL2 Antigen (Recombinant Protein)
别 名： ORP2; ORP-2; DFNA67; DNFA67
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Fusion protein corresponding to a region derived from 281-480 amino acids of human OSBPL2 |
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Full name: |
oxysterol binding protein like 2 |
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Synonyms: |
ORP2; ORP-2; DFNA67; DNFA67 |
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Swissprot: |
Q9H1P3 |
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Gene Accession: |
BC000296 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. |
