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中文名称： MAP4 抗原（重组蛋白）
英文名称： MAP4 Antigen (Recombinant Protein)
相关类别： 抗原
储 存： 冷冻（-20℃）
概 述
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Fusion protein corresponding to N terminal 151 amino acids of human MAP4 |
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Full name: |
microtubule-associated protein 4 |
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Swissprot: |
P27816 |
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Gene Accession: |
BC008715 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. |
