中文名称: 兔抗TUBGCP4多克隆抗体
Background: |
This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants. |
Applications: |
ELISA, WB |
Name of antibody: |
TUBGCP4 |
Immunogen: |
Fusion protein of human TUBGCP4 |
Full name: |
tubulin gamma complex associated protein 4 |
Synonyms: |
76P; GCP4; GCP-4; Grip76; MCCRP3 |
SwissProt: |
Q9UGJ1 |
ELISA Recommended dilution: |
5000-10000 |
WB Predicted band size: |
76 kDa |
WB Positive control: |
HT-29, NIH/3T3, 231, Hela, RAW264.7, K562 and LOVO cell lysates |
WB Recommended dilution: |
500-2000 |