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  • LILRB2抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW18246
    • 应用 : 仅供科研使用
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    • 货期 : 现货
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中文名称:LILRB2抗原(重组蛋白)

英文名称: LILRB2 Antigen (Recombinant Protein)

别      名: ILT4; LIR2; CD85D; ILT-4; LIR-2; MIR10; MIR-10

储      存: 冷冻(-20℃)

相关类别: 抗原

概      述

Fusion protein corresponding to a region derived from 483-598 amino acids of human LILRB2


技术规格

Full name:

leukocyte immunoglobulin like receptor B2

Synonyms:

ILT4; LIR2; CD85D; ILT-4; LIR-2; MIR10; MIR-10

Swissprot:

Q8N423

Gene Accession:

BC036827

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.