中文名称: 兔抗MECP2多克隆抗体
英文名称: Anti-MECP2 rabbit polyclonal antibody
别 名: RS; RTS; RTT; PPMX; MRX16; MRX79; MRXSL; AUTSX3; MRXS13
相关类别: 一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
抗 原: MECP2
反应种属: Human, Mouse, Rat
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background: |
DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
MECP2 |
Immunogen: |
Fusion protein of human MECP2 |
Full name: |
methyl CpG binding protein 2 |
Synonyms: |
RS; RTS; RTT; PPMX; MRX16; MRX79; MRXSL; AUTSX3; MRXS13 |
SwissProt: |
P51608 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human esophagus cancer and Human brain |
IHC Recommend dilution: |
100-300 |
WB Predicted band size: |
52 kDa |
WB Positive control: |
Mouse lung tissue |
WB Recommended dilution: |
200-1000 |