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中文名称： LDOC1 抗原（重组蛋白）
英文名称： LDOC1 Antigen (Recombinant Protein)
别 名： leucine zipper, down-regulated in cancer 1; Mar7; BCUR1; Mart7
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述
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Fusion protein corresponding to N terminal 132 amino acids of human LDOC1 |
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Full name: |
leucine zipper, down-regulated in cancer 1 |
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Synonyms: |
Mar7; BCUR1; Mart7 |
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Swissprot: |
O95751 |
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Gene Accession: |
BC003104 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. |
