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中文名称： LBR 抗原（重组蛋白）
英文名称： LBR Antigen (Recombinant Protein)
别 名： lamin B receptor; PHA; LMN2R; TDRD18; DHCR14B
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述
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Fusion protein corresponding to N terminal 210 amino acids of human LBR |
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Full name: |
lamin B receptor |
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Synonyms: |
PHA; LMN2R; TDRD18; DHCR14B |
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Swissprot: |
Q14739 |
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Gene Accession: |
BC020079 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. |
