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中文名称：KRT8抗原（重组蛋白）
英文名称： KRT8 Antigen (Recombinant Protein)
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述
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Fusion protein corresponding to a region derived from 205-483 amino acids of human KRT8 |
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Full name: |
keratin 8 |
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Synonyms: |
K8; KO; CK8; CK-8; CYK8; K2C8; CARD2 |
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Swissprot: |
P05787 |
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Gene Accession: |
BC008200 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. |
