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  • 兔抗MCM3多克隆抗体

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    • 品牌 : 通蔚生物
    • 目录号 : TW18175
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称:   兔抗MCM3多克隆抗体


英文名称:   Anti-MCM3 rabbit polyclonal antibody


别      名:   HCC5, P1.h, RLFB, P1-MCM3


抗     原:   MCM3


储     存:   冷冻(-20℃)


宿      主:   Rabbit


相关类别:  一抗


反应种属:  Human, Mouse


标  记  物:  Unconjugate


克隆类型:  rabbit polyclonal


技术规格

Background:

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

MCM3

Immunogen:

Fusion protein of human MCM3

Full name:

minichromosome maintenance complex component 3

Synonyms:

HCC5, P1.h, RLFB, P1-MCM3

SwissProt:

P25205

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human lung cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

91 kDa

WB Positive control:

K562, Jurkat, hela and 293T cells

WB Recommended dilution:

500-2000