中文名称: 兔抗MCM3多克隆抗体
英文名称: Anti-MCM3 rabbit polyclonal antibody
别 名: HCC5, P1.h, RLFB, P1-MCM3
抗 原: MCM3
储 存: 冷冻(-20℃)
宿 主: Rabbit
相关类别: 一抗
反应种属: Human, Mouse
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background: |
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
MCM3 |
Immunogen: |
Fusion protein of human MCM3 |
Full name: |
minichromosome maintenance complex component 3 |
Synonyms: |
HCC5, P1.h, RLFB, P1-MCM3 |
SwissProt: |
P25205 |
ELISA Recommended dilution: |
1000-5000 |
IHC positive control: |
Human lung cancer |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
91 kDa |
WB Positive control: |
K562, Jurkat, hela and 293T cells |
WB Recommended dilution: |
500-2000 |