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  • POT1抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW18147
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称: POT1抗原(重组蛋白)

英文名称: POT1 Antigen (Recombinant Protein)

别       名: protection of telomeres 1; CMM10; HPOT1

储       存: 冷冻(-20℃)

相关类别: 抗原

概述

Fusion protein corresponding to a region derived from 385-634 amino acids of human POT1

技术规格

Full name:

protection of telomeres 1

Synonyms:

CMM10; HPOT1

Swissprot:

Q9NUX5

Gene Accession:

BC002923

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.