欢迎来到上海通蔚!

021-54845833/15800441009

品质保证 · 通蔚试剂

当前位置: 首页 > 科研产品 > 科研抗体 > 其他抗体 > PLGLB2抗原(重组蛋白)

产品中心

  • PLGLB2抗原(重组蛋白)

    规格:
    数量:

    购买数量

    价格:
    • 品牌 : 通蔚生物
    • 目录号 : TW18121
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
    • 商品库存:40
  • 商品详情
  • 参考文献
  • 说明书下载
  • 商品评论0
  • 相关产品

中文名称:PLGLB2抗原(重组蛋白)

英文名称: PLGLB2 Antigen (Recombinant Protein)

别       名: plasminogen-like B2; PLGP1

储       存: 冷冻(-20℃)

相关类别: 抗原

概述

Fusion protein corresponding to a region derived from 20-96 amino acids of human PLGLB2

技术规格

Full name:

plasminogen-like B2

Synonyms:

PLGP1

Swissprot:

Q02325

Gene Accession:

BC005379

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Cleavage of the serine proteinase plasminogen to form plasmin is the central event in the dissolution of blood clots by the fibrinolytic system. Within the fibrinolytic cascade, the serine proteinases urokinase-type plasminogen activator (uPA) and tissue-type plasminogen activator (tPA) activate the proenzyme plasminogen by cleaving plasminogen to form the fibrinolytically active enzyme plasmin. PLGLB2 (plasminogen-like B2), also known as PLGP1, is a 96 amino acid protein that resembles the N-terminal plasminogen activation peptide, which is released from plasminogen during conversion to plasmin. PLGLB2 may bind to lysine binding sites present in the kringle structures of plasminogen, an event that interfers with the binding of fibrin or α-2 antiplasmin to plasminogen and may result in the localization of activity at sites necessary for extracellular matrix destruction.