兔抗DEFA1B多克隆抗体

Background:

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. Two transcript variants encoding different isoforms have been found for this gene.

Applications:

ELISA, WB, IHC

Name of antibody:

DEFA1B

Immunogen:

Synthetic peptide of human DEFA1B

Full name:

defensin alpha 1B

Synonyms:

HP1; HP-1; HNP-1

SwissProt:

P59665

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human thyroid cancer and Human liver cancer

IHC Recommend dilution:

25-100

WB Predicted band size:

10 kDa

WB Positive control:

Human left kidney tissue

WB Recommended dilution:

200-1000