中文名称:IRF6抗原(重组蛋白)
英文名称: IRF6 Antigen (Recombinant Protein)
别 名: LPS; PIT; PPS; VWS; OFC6; PPS1; VWS1
储 存: 冷冻(-20℃)
相关类别: 抗原
概述
Fusion protein corresponding to C terminal 301 amino acids of human IRF6 |
Full name: |
interferon regulatory factor 6 |
Synonyms: |
LPS; PIT; PPS; VWS; OFC6; PPS1; VWS1 |
Swissprot: |
O14896 |
Gene Accession: |
BC014852 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants. |