兔抗DDX39A多克隆抗体

Background:

This gene encodes a member of the DEAD box protein family. These proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is thought to play a role in the prognosis of patients with gastrointestinal stromal tumors. A pseudogene of this gene is present on chromosome 13. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Applications:

ELISA, WB, IHC

Name of antibody:

DDX39A

Immunogen:

Fusion protein of human DDX39A

Full name:

DExD-box helicase 39A

Synonyms:

BAT1; DDXL; BAT1L; DDX39; URH49

SwissProt:

O00148

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer and Human lung cancer

IHC Recommend dilution:

50-200

WB Predicted band size:

49 kDa

WB Positive control:

231 and Jurkat cell lysates

WB Recommended dilution:

500-2000