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    OLFM3抗原（重组蛋白）

    OLFM3抗原（重组蛋白）

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    • 品牌 : 通蔚生物
    • 目录号 : TW17898
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称： OLFM3抗原（重组蛋白）

英文名称： OLFM3 Antigen (Recombinant Protein)

别      名： olfactomedin 3; NOE3; NOELIN3; OPTIMEDIN

储       存： 冷冻（-20℃）

相关类别： 抗原

概述

Fusion protein corresponding to C terminal 250 amino acids of human OLFM3

技术规格

Full name:

olfactomedin 3

Synonyms:

NOE3; NOELIN3; OPTIMEDIN

Swissprot:

Q96PB7

Gene Accession:

BC022531

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

OLFM3 (olfactomedin 3), also known as NOE3, is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.