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中文名称：IGSF8抗原（重组蛋白）
英文名称： IGSF8 Antigen (Recombinant Protein)
别 名： EWI2; PGRL; CD316; EWI-2; KCT-4; CD81P3; LIR-D1
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
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Fusion protein corresponding to a region derived from 242-475 amino acids of human IGSF8 |
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Full name: |
immunoglobulin superfamily, member 8 |
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Synonyms: |
EWI2; PGRL; CD316; EWI-2; KCT-4; CD81P3; LIR-D1 |
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Swissprot: |
Q969P0 |
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Gene Accession: |
BC053881 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein. |
