Background: |
This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
DDOST |
Immunogen: |
Fusion protein of human DDOST |
Full name: |
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit |
Synonyms: |
OST; WBP1; AGER1; CDG1R; OST48; OKSWcl45 |
SwissProt: |
P39656 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human liver cancer |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
51 kDa |
WB Positive control: |
A172, HepG2 and LOVO cell lysates |
WB Recommended dilution: |
200-1000 |