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中文名称：TRIP4抗原（重组蛋白）
英文名称： TRIP4 Antigen (Recombinant Protein)
别 名： ASC1; ASC-1; HsT17391
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to C terminal 250 amino acids of human TRIP4 |
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Full name: |
thyroid hormone receptor interactor 4 |
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Synonyms: |
ASC1; ASC-1; HsT17391 |
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Swissprot: |
Q15650 |
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Gene Accession: |
BC012448 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Activating signal co-integrator-1 (ASC-1), originally identified as TRIP4, is a transcriptional co-activator of nuclear receptors that associates with specific components of the RNA polymerase II complex and binds the basal transcription factors TBP and TFIIA. ASC-1 functions with the transcription integrators SRC-1 and CBP/p300 through its zinc finger motif and is dependent on their ligand-dependent transactivation domain, AF2. Endogenous ASC-1 in HeLa cells is predominantly a nuclear protein. Under conditions of serum starvation, ASC-1 localizes to the cytoplasm. |
