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中文名称：TRAFD1 抗原（重组蛋白）
英文名称： TRAFD1 Antigen (Recombinant Protein)
别 名： TRAF-type zinc finger domain containing 1; FLN29
储 存： 冷冻（-20℃）
相关类别：抗原
概 述：
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Fusion protein corresponding to C terminal 250 amino acids of human TRAFD1 |
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Full name: |
TRAF-type zinc finger domain containing 1 |
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Synonyms: |
FLN29 |
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Swissprot: |
O14545 |
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Gene Accession: |
BC003553 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses. Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. |
