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中文名称：TRAF3IP2 抗原（重组蛋白）
英文名称： TRAF3IP2 Antigen (Recombinant Protein)
别 名： TRAF3 interacting protein 2; ACT1; CIKS; C6orf2; C6orf4; C6orf5; C6orf6; PSORS13
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Fusion protein corresponding to a region derived from 1-256 amino acids of human TRAF3IP2 |
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Full name: |
TRAF3 interacting protein 2 |
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Synonyms: |
ACT1; CIKS; C6orf2; C6orf4; C6orf5; C6orf6; PSORS13 |
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Swissprot: |
O43734 |
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Gene Accession: |
BC002823 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene. |
