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中文名称：TRAF2 抗原（重组蛋白）
英文名称： TRAF2 Antigen (Recombinant Protein)
别 名： TNF receptor-associated factor 2; TRAP; TRAP3; MGC:45012
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 351-496 amino acids of human TRAF2 |
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Full name: |
TNF receptor-associated factor 2 |
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Synonyms: |
TRAP; TRAP3; MGC:45012 |
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Swissprot: |
Q12933 |
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Gene Accession: |
BC032410 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. |
