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  • NFKBID抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW17756
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称:NFKBID抗原(重组蛋白)

英文名称: NFKBID Antigen (Recombinant Protein)

储       存: 冷冻(-20℃)

相关类别: 抗原

概述

Fusion protein corresponding to a region derived from 1-221 amino acids of human NFKBID

技术规格

Full name:

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta

Synonyms:

TA-NFKBH, IkappaBNS

Swissprot:

Q8NI38

Gene Accession:

BC006273

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.IκBNS, the nuclear IκB-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.IκBNS has been identified as a member of the IκB family of NF-κB inhibitors, which undergoes induction upon TCR signaling. IκBNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine.