ELISA试剂盒

PCR试剂盒

生化试剂盒

细胞系

细胞库

基础培养基

完全培养基

原代细胞

细胞专用培养基

菌株

科研抗体

生化试剂

病理染色液

食品检测类试剂盒

NFKB1抗原（重组蛋白）

规格：

数量：

购买数量

价格：￥

中文名称：NFKB1抗原（重组蛋白）

英文名称： NFKB1 Antigen (Recombinant Protein)

储存： 冷冻（-20℃）

相关类别：抗原

概述

Fusion protein corresponding to a region derived from 619-968 amino acids of human NFKB1

技术规格

Full name:	nuclear factor kappa B subunit 1
Synonyms:	p50; KBF1; p105; EBP-1; CVID12; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B1
Swissprot:	P19838
Gene Accession:	BC051765
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.

ELISA试剂盒

PCR试剂盒