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    NECTIN4抗原（重组蛋白）

    NECTIN4抗原（重组蛋白）

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    • 品牌 : 通蔚生物
    • 目录号 : TW17736
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中文名称： NECTIN4抗原（重组蛋白）

英文名称： NECTIN4 Antigen (Recombinant Protein)

别       名： nectin cell adhesion molecule 4; LNIR; PRR4; EDSS1; PVRL4; nectin-4

储       存： 冷冻（-20℃）

相关类别： 抗原

概述

Fusion protein corresponding to a region derived from 371-510 amino acids of human NECTIN4

技术规格

Full name:

nectin cell adhesion molecule 4

Synonyms:

LNIR; PRR4; EDSS1; PVRL4; nectin-4

Swissprot:

Q96NY8

Gene Accession:

BC010423

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011]