NDUFS8抗原（重组蛋白）

Full name:

NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa

Synonyms:

TYKY; CI-23k; CI23KD

Swissprot:

O00217

Gene Accession:

BC119754

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of two of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome.