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中文名称：STK17B抗原（重组蛋白）
英文名称： STK17B Antigen (Recombinant Protein)
别 名： DRAK2
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 33-293 amino acids of human STK17B |
|
Full name: |
serine/threonine kinase 17b |
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Synonyms: |
DRAK2 |
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Swissprot: |
O94768 |
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Gene Accession: |
BC016040 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The full-length STK17B cDNA clone encodes a deduced 372-amino acid protein with a molecular mass of 42.34 kD. The putative kinase domain is located at the N terminus and contains all 11 subdomains conserved among ser/thr kinases. STK17A and STK17B share 59.7% amino acid identity. Northern blot analysis revealed that STK17B was expressed in various tissues, such as heart, placenta, liver, and pancreas, as different-sized transcripts, presumably due to differences in the 3-prime untranslated region. Transient transfection of COS-7 cells showed that STK17B localized in nuclei. Phosphorylates myosin light chains. Acts as a positive regulator of apoptosis. |
