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中文名称：STAMBP 抗原（重组蛋白）
英文名称： STAMBP Antigen (Recombinant Protein)
别 名： STAM binding protein; AMSH
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 252-361 amino acids of human STAMBP |
|
Full name: |
STAM binding protein |
|
Synonyms: |
AMSH |
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Swissprot: |
O95630 |
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Gene Accession: |
BC065574 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. |
