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Fusion protein corresponding to a region derived from 97-350 amino acids of human PTPN7 |
Full name:
protein tyrosine phosphatase, non-receptor type 7
Synonyms:
LPTP; HEPTP; PTPNI; BPTP-4; LC-PTP
Swissprot:
P35236
Gene Accession:
BC001746
Purity:
>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:
Escherichia coli
Tags:
His tag C-Terminus, GST tag N-Terminus
Background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities.
