Fusion protein corresponding to N terminal 170 amino acids of human PTP4A1 |
Full name: |
protein tyrosine phosphatase type IVA, member 1 |
Synonyms: |
HH72; PRL1; PRL-1; PTPCAAX1; PTP(CAAX1) |
Swissprot: |
Q93096 |
Gene Accession: |
BC023975 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of a small class of prenylated protein tyrosine phosphatases (PTPs), which contain a PTP domain and a characteristic C-terminal prenylation motif. The encoded protein is a cell signaling molecule that plays regulatory roles in a variety of cellular processes, including cell proliferation and migration. The protein may also be involved in cancer development and metastasis. This tyrosine phosphatase is a nuclear protein, but may associate with plasma membrane by means of its prenylation motif. Pseudogenes related to this gene are located on chromosomes 1, 2, 5, 7, 11 and X. |