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中文名称： PTK6抗原（重组蛋白）
英文名称： PTK6 Antigen (Recombinant Protein)
别 名： BRK
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 224-445 amino acids of human PTK6 |
|
Full name: |
protein tyrosine kinase 6 |
|
Synonyms: |
BRK |
|
Swissprot: |
Q13882 |
|
Gene Accession: |
BC035843 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. |
