中文名称:HK1抗原(重组蛋白)
英文名称: HK1 Antigen (Recombinant Protein)
别 名: HKD; HKI; HXK1; HMSNR; HK1-ta; HK1-tb; HK1-tc
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
Fusion protein corresponding to a region derived from 320-481 amino acids of human HK1 |
Full name: |
hexokinase 1 |
Synonyms: |
HKD; HKI; HXK1; HMSNR; HK1-ta; HK1-tb; HK1-tc |
Swissprot: |
P19367 |
Gene Accession: |
BC008730 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. |