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中文名称： GCKR抗原（重组蛋白）
英文名称： GCKR Antigen (Recombinant Protein)
别 名： GKRP; FGQTL5
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 90-286 amino acids of human GCKR |
|
Full name: |
glucokinase (hexokinase 4) regulator |
|
Synonyms: |
GKRP; FGQTL5 |
|
Swissprot: |
Q14397 |
|
Gene Accession: |
BC130481 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). |
