中文名称:FZD4 抗原(重组蛋白)
英文名称: FZD4 Antigen (Recombinant Protein)
别 名: Frizzled family receptor 4; Fz4; EVR1; FEVR; Fz-4; FzE4; GPCR; hFz4; CD344; FZD4S
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
Fusion protein corresponding to a region derived from 37-222 amino acids of human FZD4 |
Full name: |
Frizzled family receptor 4 |
Synonyms: |
Fz4; EVR1; FEVR; Fz-4; FzE4; GPCR; hFz4; CD344; FZD4S |
Swissprot: |
Q9ULV1 |
Gene Accession: |
BC114527 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. |