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中文名称： FLI1抗原（重组蛋白）
英文名称： FLI1 Antigen (Recombinant Protein)
别 名： EWSR2; SIC-1; BDPLT21
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Fusion protein corresponding to a region derived from 203-452 amino acids of human FLI1 |
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Full name: |
Fli-1 proto-oncogene, ETS transcription factor |
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Synonyms: |
EWSR2; SIC-1; BDPLT21 |
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Swissprot: |
Q01543 |
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Gene Accession: |
BC001670 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] |
