中文名称: FES抗原(重组蛋白)
英文名称: FES Antigen (Recombinant Protein)
别 名: FPS
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
Fusion protein corresponding to C terminal 250 amino acids of human FES |
Full name: |
feline sarcoma oncogene |
Synonyms: |
FPS |
Swissprot: |
P07332 |
Gene Accession: |
BC035357 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms. |