中文名称: FCAR抗原(重组蛋白)
英文名称: FCAR Antigen (Recombinant Protein)
别 名: CD89
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
Fusion protein corresponding to a region derived from 22-227 amino acids of human FCAR |
Full name: |
Immunoglobulin alpha Fc receptor |
Synonyms: |
CD89 |
Swissprot: |
P24071 |
Gene Accession: |
BC027953 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. |