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    SPATA17抗原（重组蛋白）

    SPATA17抗原（重组蛋白）

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    • 品牌 : 通蔚生物
    • 目录号 : TW17256
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称： SPATA17抗原（重组蛋白）

英文名称： SPATA17 Antigen (Recombinant Protein)

别       名： IQCH, MSRG11, MSRG-11, RP11-144C20.1
储       存： 冷冻（-20℃）
相关类别： 抗原

概述

Fusion protein corresponding to C terminal 300 amino acids of human SPATA17

技术规格

Full name:

spermatogenesis associated 17

Synonyms:

IQCH, MSRG11, MSRG-11, RP11-144C20.1

Swissprot:

Q96L03

Gene Accession:

BC014608

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Spata17 gene, which called MSRG11, by digital differential display of ESTs found only in testis. The deduced 292-amino acid protein was considered to be a member of the family of calmodulin (CaM)-binding proteins because it contained 3 short CaM-binding motifs containing conserved ile and gln residues (IQ motif). Spata17 protein was most abundant in the cytoplasm of round spermatids and elongating spermatids within seminiferous tubules of the adult testis. Expression gradually decreased in the manipulated testis of animals that underwent experimental unilateral cryptorchidism. Transient transfection experiments with a Spata17 expression construct in cultured spermatogonia GC-1 cells indicated that Spata17 accelerated apoptosis in a dose-dependent manner.