中文名称: ENO1抗原(重组蛋白)
英文名称: ENO1 Antigen (Recombinant Protein)
别 名: NNE; PPH; MPB1; ENO1L1
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
Fusion protein corresponding to C terminal 250 amino acids of human ENO1 |
Full name: |
enolase 1, (alpha) |
Synonyms: |
NNE; PPH; MPB1; ENO1L1 |
Swissprot: |
P06733 |
Gene Accession: |
BC001810 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes alpha-enolase, one of three enolase isoenzymes found in mammals. Each isoenzyme is a homodimer composed of 2 alpha, 2 gamma, or 2 beta subunits, and functions as a glycolytic enzyme. Alpha-enolase in addition, functions as a structural lens protein (tau-crystallin) in the monomeric form. Alternative splicing of this gene results in a shorter isoform that has been shown to bind to the c-myc promoter and function as a tumor suppressor. Several pseudogenes have been identified, including one on the long arm of chromosome 1. Alpha-enolase has also been identified as an autoantigen in Hashimoto encephalopathy. |