兔抗DCTN2多克隆抗体

Background:

This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits.

Applications:

ELISA, WB, IHC

Name of antibody:

DCTN2

Immunogen:

Fusion protein of human DCTN2

Full name:

dynactin 2 (p50)

Synonyms：

RBP50; DCTN50; HEL-S-77; DYNAMITIN

SwissProt:

Q13561

ELISA Recommended dilution:

2000-10000

IHC positive control:

Human liver cancer and human cervical cancer

IHC Recommend dilution:

100-300

WB Predicted band size:

44 kDa

WB Positive control:

293T cells and mouse brain tissue

WB Recommended dilution:

200-1000