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  • SIRT3抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW17181
    • 应用 : 仅供科研使用
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    • 货期 : 现货
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中文名称: SIRT3抗原(重组蛋白)

英文名称: SIRT3 Antigen (Recombinant Protein)

别      名: SIR2L3

储      存: 冷冻(-20℃)

相关类别: 抗原

概述

Fusion protein corresponding to a region derived from 126-382 amino acids of human SIRT3

技术规格

Full name:

Sirtuin 3

Synonyms:

SIR2L3

Swissprot:

Q9NTG7

Gene Accession:

BC001042

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.