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    SELENOM抗原（重组蛋白）

    SELENOM抗原（重组蛋白）

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    • 品牌 : 通蔚生物
    • 目录号 : TW17159
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
    • 商品库存：40
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中文名称： SELENOM抗原（重组蛋白）

英文名称： SELENOM Antigen (Recombinant Protein)

别       名： SELM; SEPM

储       存： 冷冻（-20℃）

相关类别： 抗原

概述

Fusion protein corresponding to a region derived from 59-145 amino acids of human SELENOM

技术规格

Full name:

selenoprotein M

Synonyms:

SELM; SEPM

Swissprot:

Q8WWX9

Gene Accession:

BC013421

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene belongs to the selenoprotein M/SEP15 family. The exact function of this protein is not known. It is localized in the perinuclear region, is highly expressed in the brain, and may be involved in neurodegenerative disorders. Transgenic mice with targeted deletion of this gene exhibit increased weight gain, suggesting a role for this gene in the regulation of body weight and energy metabolism. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal.