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021-54845833/15800441009
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Background: |
This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. |
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Applications: |
ELISA, WB |
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Name of antibody: |
TSLP |
|
Immunogen: |
Fusion protein of human TSLP |
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Full name: |
Thymic stromal lymphopoietin |
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SwissProt: |
Q969D9 |
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ELISA Recommended dilution: |
2000-5000 |
|
WB Predicted band size: |
18 kDa |
|
WB Positive control: |
Jurkat cells |
|
WB Recommended dilution: |
500-2000 |
|
Background: |
This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. |
|
Applications: |
ELISA, WB |
|
Name of antibody: |
TSLP |
|
Immunogen: |
Fusion protein of human TSLP |
|
Full name: |
Thymic stromal lymphopoietin |
|
SwissProt: |
Q969D9 |
|
ELISA Recommended dilution: |
2000-5000 |
|
WB Predicted band size: |
18 kDa |
|
WB Positive control: |
Jurkat cells |
|
WB Recommended dilution: |
500-2000 |
