兔抗TSLP多克隆抗体

Background:

This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants.

Applications:

ELISA, WB

Name of antibody:

TSLP

Immunogen:

Fusion protein of human TSLP

Full name:

Thymic stromal lymphopoietin

SwissProt:

Q969D9

ELISA Recommended dilution:

2000-5000

WB Predicted band size:

18 kDa

WB Positive control:

Jurkat cells

WB Recommended dilution:

500-2000

Background:

This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants.

Applications:

ELISA, WB

Name of antibody:

TSLP

Immunogen:

Fusion protein of human TSLP

Full name:

Thymic stromal lymphopoietin

SwissProt:

Q969D9

ELISA Recommended dilution:

2000-5000

WB Predicted band size:

18 kDa

WB Positive control:

Jurkat cells

WB Recommended dilution:

500-2000