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    PTHLH抗原（重组蛋白）

    PTHLH抗原（重组蛋白）

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    • 品牌 : 通蔚生物
    • 目录号 : TW17126
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称： PTHLH抗原（重组蛋白）

英文名称： PTHLH Antigen (Recombinant Protein)

别       名： HHM, PLP, BDE2, PTHR, PTHRP

储       存： 冷冻（-20℃）

相关类别： 抗原

概述

Fusion protein corresponding to a region derived from 37-177 amino acids of human PTHLH

技术规格

Full name:

parathyroid hormone-like hormone

Synonyms:

HHM, PLP, BDE2, PTHR, PTHRP

Swissprot:

P12272

Gene Accession:

BC005961

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone.