购物车
帮助
021-54845833/15800441009
中文名称：DNTT 抗原（重组蛋白）
英文名称： DNTT Antigen (Recombinant Protein)
别 名： DNA nucleotidylexotransferase; TDT
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 260-509 amino acids of human DNTT |
|
Full name: |
DNA nucleotidylexotransferase |
|
Synonyms: |
TDT |
|
Swissprot: |
P04053 |
|
Gene Accession: |
BC012920 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. |
