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    PSMD7抗原（重组蛋白）

    PSMD7抗原（重组蛋白）

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    • 品牌 : 通蔚生物
    • 目录号 : TW17103
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中文名称： PSMD7抗原（重组蛋白）

英文名称： PSMD7 Antigen (Recombinant Protein)

别       名： P40, S12, Rpn8, MOV34

储       存： 冷冻（-20℃）

相关类别： 抗原

概述

Fusion protein corresponding to C terminal 250 amino acids of human PSMD7

技术规格

Full name:

proteasome (prosome, macropain) 26S subunit, non-ATPase, 7

Synonyms:

P40, S12, Rpn8, MOV34

Swissprot:

P51665

Gene Accession:

BC012606

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.