ELISA试剂盒

PCR试剂盒

生化试剂盒

细胞系

细胞库

基础培养基

完全培养基

原代细胞

细胞专用培养基

菌株

科研抗体

生化试剂

病理染色液

食品检测类试剂盒

PRCP抗原（重组蛋白）

规格：

数量：

购买数量

价格：￥

品牌 : 通蔚生物
目录号 : TW17073
应用 : 仅供科研使用
保存条件 : 低温保存
货期 : 现货
商品库存：40

中文名称： PRCP抗原（重组蛋白）

英文名称： PRCP Antigen (Recombinant Protein)

别名： PCP; HUMPCP

储存： 冷冻（-20℃）

相关类别：抗原

概述

Fusion protein corresponding to a region derived from 46-317 amino acids of human PRCP

技术规格

Full name:

Prolylcarboxypeptidase (angiotensinase C)

Synonyms:

PCP; HUMPCP

Swissprot:

P42785

Gene Accession:

BC001500

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

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