中文名称: DEGS1抗原(重组蛋白)
英文名称: DEGS1 Antigen (Recombinant Protein)
别 名: MLD; DEGS; DES1; Des-1; FADS7; MIG15; DEGS-1
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
Fusion protein corresponding to a region derived from 230-323 amino acids of human DEGS1 |
Full name: |
delta(4)-desaturase, sphingolipid 1 |
Synonyms: |
MLD; DEGS; DES1; Des-1; FADS7; MIG15; DEGS-1 |
Swissprot: |
O15121 |
Gene Accession: |
BC000961 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. |