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  • POU5F1抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW17066
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
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中文名称: POU5F1抗原(重组蛋白)

英文名称: POU5F1 Antigen (Recombinant Protein)

别      名: OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4

储      存: 冷冻(-20℃)

相关类别: 抗原

概述

Fusion protein corresponding to a region derived from 1-150 amino acids of human POU5F1

技术规格

Full name:

POU class 5 homeobox 1

Synonyms:

OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4

Swissprot:

Q01860

Gene Accession:

BC117435

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.