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  • PIK3R1抗原(重组蛋白)

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    • 品牌 : 通蔚生物
    • 目录号 : TW17045
    • 应用 : 仅供科研使用
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中文名称:PIK3R1抗原(重组蛋白)

英文名称: PIK3R1 Antigen (Recombinant Protein)

别      名: p85, GRB1, p85-ALPHA

储      存: 冷冻(-20℃)

相关类别: 抗原

概述

Fusion protein corresponding to a region derived from 113-301 amino acids of human PIK3R1

技术规格

Full name:

phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

Synonyms:

p85, GRB1, p85-ALPHA

Swissprot:

P27986

Gene Accession:

BC030815

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms.