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    PEG10抗原（重组蛋白）

    PEG10抗原（重组蛋白）

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    • 品牌 : 通蔚生物
    • 目录号 : TW17034
    • 应用 : 仅供科研使用
    • 保存条件 : 低温保存
    • 货期 : 现货
    • 商品库存：40
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中文名称： PEG10抗原（重组蛋白）

英文名称： PEG10 Antigen (Recombinant Protein)

别       名： EDR, HB-1, Mar2, MEF3L, Mart2, RGAG3

储       存： 冷冻（-20℃）

相关类别： 抗原

概述

Fusion protein corresponding to C terminal 250 amino acids of human PEG10

技术规格

Full name:

paternally expressed 10

Synonyms:

EDR, HB-1, Mar2, MEF3L, Mart2, RGAG3

Swissprot:

Q86TG7

Gene Accession:

BC050659

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.